A2m Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comA2m Polyclonal Antibody for Mouse(Mus musculus)

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A2m (Gene name),

Alpha-2-macroglobulin (Protein name ), A2M_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

A2m(Pzp);

Protein name:

Alpha-2-macroglobulin(Alpha-2-M);

Alternative:

Pregnancy zone protein;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

1495

Sequence:

50:

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1300:

1350:

1400:

1450:

1495:

AVEQDIPVKN | LKPAPIKVYD | YYETDEFTVE | EYSAPFSDGS | EQGNA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.260144

Pfam:

PF00207

SMR:

Q61838

String:

Q61838

KEGG:

mmu:11287

Uniprot:

Q61838

FOR

ELISA Kit for Mouse Alpha-2-M

Cat.:

E1017r

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Packing:

96T

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ELISA Kit for Mouse Alpha-2-M

Cat.:

E1017b

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96T

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ELISA Kit for Mouse Alpha-2-M

Cat.:

E1017m

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96T

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ELISA Kit for Mouse Alpha-2-M

Cat.:

E1017h

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96T

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CLIA Kit for Mouse Alpha-2-M

Cat.:

U1017h

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Packing:

96T

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CLIA Kit for Mouse Alpha-2-M

Cat.:

U1017m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Alpha-2-M

Cat.:

U1017b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Alpha-2-M

Cat.:

U1017r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Alpha-2-M

Cat.:

P1017Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Alpha-2-M

Cat.:

P1017Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Alpha-2-M

Cat.:

P1017Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Alpha-2-M

Protein for Mouse Alpha-2-M

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The primary sequence and the subunit structure of mouse alpha-2-macroglobulin, deduced from protein sequencing of the isolated subunits and from molecular cloning of the cDNA."
van Leuven F. , Torrekens S. , Overbergh L. , Lorent K. , de Strooper B. , van den Berghe H.
Eur. J. Biochem.210:319-327(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 25-44 AND 1240-1259
tissue: Liver.
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Liver.
4.

"Molecular cloning of the mouse gene coding for alpha 2-macroglobulin and targeting of the gene in embryonic stem cells."
Umans L. , Serneels L. , Hilliker C. , Stas L. , Overbergh L. , de Strooper B. , van Leuven F. , van den Berghe H.
Genomics22:519-529(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-161
strain: 129/J.
5.

"Characterization of a murine alpha 2 macroglobulin gene expressed in reproductive and cardiovascular tissue."
He H. , McCartney D.J. , Wei Q. , Esadeg S. , Zhang J. , Foster R.A. , Hayes M.A. , Tayade C. , Van Leuven F. , Croy B.A.
Biol. Reprod.72:266-275(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
strain: C57BL/6.
tissue: Placenta.
6.

"Proteome-wide characterization of N-glycosylation events by diagonal chromatography."
Ghesquiere B. , Van Damme J. , Martens L. , Vandekerckhove J. , Gevaert K.
J. Proteome Res.5:2438-2447(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-157; ASN-405; ASN-412; ASN-1003; ASN-1385 AND ASN-1443
strain: C57BL/6.
tissue: Plasma.
7.

"Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides."
Bernhard O.K. , Kapp E.A. , Simpson R.J.
J. Proteome Res.6:987-995(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-157; ASN-568; ASN-881; ASN-1003; ASN-1385 AND ASN-1443
strain: C57BL/6.
tissue: Plasma.

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